STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF59151.1PFAM: formyl transferase domain protein; KEGG: nmr:Nmar_0223 formyl transferase domain-containing protein. (281 aa)    
Predicted Functional Partners:
purD
KEGG: pth:PTH_2540 phosphoribosylamine-glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family.
 
  
 0.964
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: pca:Pcar_1293 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
 
  
 0.926
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.917
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
  
0.787
EEF59462.1
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: bha:BH1629 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
    
 0.785
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.733
EEF59900.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.729
EEF57331.1
Methionine synthase; KEGG: lbj:LBJ_4091 B12-dependent methionine synthase; TIGRFAM: methionine synthase; PFAM: dihydropteroate synthase DHPS; homocysteine S-methyltransferase; Methionine synthase B12-binding module cap domain protein; Vitamin B12 dependent methionine synthase activation region; cobalamin B12-binding domain protein.
    
  0.721
EEF63199.1
Methionine synthase I (cobalamin-dependent) methyltransferase domain-like protein; KEGG: lch:Lcho_3268 homocysteine S-methyltransferase.
    
  0.721
EEF61950.1
KEGG: noc:Noc_1238 molybdopterin oxidoreductase, iron-sulfur binding subunit.
    
  0.718
Your Current Organism:
Pedosphaera parvula
NCBI taxonomy Id: 320771
Other names: P. parvula Ellin514, Pedosphaera parvula Ellin514, Pedosphaera parvula str. Ellin514, Pedosphaera parvula strain Ellin514, bacterium Ellin514
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.