STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF61751.1PFAM: DNA gyrase/topoisomerase IV subunit A; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A. (701 aa)    
Predicted Functional Partners:
EEF61752.1
PFAM: ATP-binding region ATPase domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II; KEGG: pcu:pc0350 DNA topoisomerase IV subunit B.
 
 0.997
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 0.986
EEF59334.1
Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit-like protein; KEGG: cth:Cthe_2376 DNA gyrase subunit B.
 
 
 0.984
EEF61753.1
Hypothetical protein.
       0.727
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.693
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
  
  
 0.569
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.538
EEF60191.1
Ferredoxin-fold anticodon-binding; KEGG: cac:CAC2356 phenylalanyl-tRNA synthetase subunit beta.
  
  
 0.510
pheT
KEGG: pca:Pcar_1423 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: t-RNA-binding domain protein; B3/4 domain protein; tRNA synthetase B5.
  
  
 0.510
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.506
Your Current Organism:
Pedosphaera parvula
NCBI taxonomy Id: 320771
Other names: P. parvula Ellin514, Pedosphaera parvula Ellin514, Pedosphaera parvula str. Ellin514, Pedosphaera parvula strain Ellin514, bacterium Ellin514
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.