Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKP50265.1Succinate dehydrogenase flavoprotein subunit. (644 aa)    
Predicted Functional Partners:
AKP50264.1
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 0.998
AKP50266.1
Succinate dehydrogenase (Or fumarate reductase) cytochrome b subunit, b558 family.
 
 0.997
AKP52050.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
 0.996
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.971
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.969
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.967
AKP52051.1
Succinate dehydrogenase flavoprotein subunit.
  
  
 
0.902
AKP50167.1
Aspartate aminotransferase.
     
 0.802
AKP51519.1
Aminotransferase class I and II.
     
 0.802
argH
Argininosuccinate lyase.
     
 0.801
Your Current Organism:
Cyclobacterium amurskyense
NCBI taxonomy Id: 320787
Other names: C. amurskyense, Cyclobacterium amurskyense Nedashkovskaya et al. 2005 emend. Hahnke et al. 2016, KCTC 12363, KMM 6143, LMG 23026, LMG:23026
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