CUH51182.1 protein (Shimia marina) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

CUH51182.1

Hypothetical protein; N-terminal double-transmembrane domain. (938 aa)

Predicted Functional Partners:

CUH51183.1

0.966

CUH51181.1

0.965

CUH51184.1

0.898

CUH51185.1

0.858

CUH53401.1

0.821

CUH51342.1

0.791

CUH54271.1

0.774

CUH51298.1

0.767

CUH51593.1

0.767

CUH53274.1

0.767

Your Current Organism:

Shimia marina

NCBI taxonomy Id: 321267
Other names: CECT 7688, DSM 26895, JCM 13038, KCCM 42117, Rhodobacteraceae bacterium CL-TA03, S. marina, Shimia marina Choi and Cho 2006, strain CL-TA03

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUH51181.1	CUH51182.1	SHM7688_00615	SHM7688_00616	Putative membrane protein.	Hypothetical protein; N-terminal double-transmembrane domain.	0.965
CUH51181.1	CUH51183.1	SHM7688_00615	SHM7688_00617	Putative membrane protein.	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	0.965
CUH51181.1	CUH51184.1	SHM7688_00615	SHM7688_00618	Putative membrane protein.	Gas vesicle protein GvpN.	0.919
CUH51181.1	CUH51185.1	SHM7688_00615	SHM7688_00619	Putative membrane protein.	Hypothetical protein.	0.817
CUH51181.1	CUH54271.1	SHM7688_00615	SHM7688_03741	Putative membrane protein.	Hypothetical protein.	0.774
CUH51182.1	CUH51181.1	SHM7688_00616	SHM7688_00615	Hypothetical protein; N-terminal double-transmembrane domain.	Putative membrane protein.	0.965
CUH51182.1	CUH51183.1	SHM7688_00616	SHM7688_00617	Hypothetical protein; N-terminal double-transmembrane domain.	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	0.966
CUH51182.1	CUH51184.1	SHM7688_00616	SHM7688_00618	Hypothetical protein; N-terminal double-transmembrane domain.	Gas vesicle protein GvpN.	0.898
CUH51182.1	CUH51185.1	SHM7688_00616	SHM7688_00619	Hypothetical protein; N-terminal double-transmembrane domain.	Hypothetical protein.	0.858
CUH51182.1	CUH51298.1	SHM7688_00616	SHM7688_00733	Hypothetical protein; N-terminal double-transmembrane domain.	Fatty acid hydroxylase superfamily protein.	0.767
CUH51182.1	CUH51342.1	SHM7688_00616	SHM7688_00777	Hypothetical protein; N-terminal double-transmembrane domain.	Diphosphomevalonate decarboxylase.	0.791
CUH51182.1	CUH51593.1	SHM7688_00616	SHM7688_01031	Hypothetical protein; N-terminal double-transmembrane domain.	Fatty acid hydroxylase superfamily protein.	0.767
CUH51182.1	CUH53274.1	SHM7688_00616	SHM7688_02727	Hypothetical protein; N-terminal double-transmembrane domain.	Fatty acid hydroxylase superfamily protein.	0.767
CUH51182.1	CUH53401.1	SHM7688_00616	SHM7688_02855	Hypothetical protein; N-terminal double-transmembrane domain.	Squalene synthase HpnD.	0.821
CUH51182.1	CUH54271.1	SHM7688_00616	SHM7688_03741	Hypothetical protein; N-terminal double-transmembrane domain.	Hypothetical protein.	0.774
CUH51183.1	CUH51181.1	SHM7688_00617	SHM7688_00615	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	Putative membrane protein.	0.965
CUH51183.1	CUH51182.1	SHM7688_00617	SHM7688_00616	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	Hypothetical protein; N-terminal double-transmembrane domain.	0.966
CUH51183.1	CUH51184.1	SHM7688_00617	SHM7688_00618	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	Gas vesicle protein GvpN.	0.980
CUH51183.1	CUH51185.1	SHM7688_00617	SHM7688_00619	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	Hypothetical protein.	0.791
CUH51183.1	CUH54271.1	SHM7688_00617	SHM7688_03741	Putative conserved protein (some members contain a von Willebrand factor type A (vWA) domain).	Hypothetical protein.	0.762

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

24

PPI enrichment p-value:

2.24e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 114

1.5

2.88

8.83e-12

GO:0019538

Protein metabolic process

11 of 319

1.1

1.52

2.64e-10

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 54

1.83

4.7

4.78e-15

GO:0019843

rRNA binding

5 of 43

1.62

1.9

2.41e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 59

1.79

4.59

2.08e-15

GO:0005622

Intracellular anatomical structure

11 of 1577

0.4

0.34

0.0010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:144

Ribosome

6 of 29

1.87

3.33

8.49e-09

CL:138

Ribosome

7 of 46

1.74

3.24

1.28e-09

CL:131

Ribosome, and Translation regulator activity

8 of 73

1.6

2.97

3.24e-10

CL:126

Ribosome, and Translation regulator activity

9 of 96

1.53

2.89

4.13e-11

CL:121

Translation, and Protein export

10 of 125

1.46

2.75

6.89e-12

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 56

1.81

4.75

1.06e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 51

1.75

3.57

6.79e-11

GOCC:0043232

Intracellular non-membrane-bounded organelle

9 of 130

1.4

2.34

4.61e-10

GOCC:0015934

Large ribosomal subunit

3 of 14

1.89

1.61

0.00053

GOCC:0043229

Intracellular organelle

10 of 337

1.03

1.29

1.69e-08

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 12

1.78

0.88

0.0188

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 59

1.79

4.56

3.06e-15

KW-0699

rRNA-binding

5 of 39

1.67

2.17

4.38e-06

KW-0488

Methylation

2 of 4

2.26

1.24

0.0048

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