node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bfmBAB | citZ | SHM7688_02923 | SHM7688_03305 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Citrate synthase 2; Belongs to the citrate synthase family. | 0.957 |
bfmBAB | fumC | SHM7688_02923 | SHM7688_03084 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.724 |
bfmBAB | gltA_3 | SHM7688_02923 | SHM7688_02987 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Citrate synthase; Belongs to the citrate synthase family. | 0.957 |
bfmBAB | icd_1 | SHM7688_02923 | SHM7688_00123 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. | 0.475 |
bfmBAB | maeB_2 | SHM7688_02923 | SHM7688_03627 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | NADP-dependent malic enzyme. | 0.993 |
bfmBAB | mdh | SHM7688_02923 | SHM7688_03756 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.958 |
bfmBAB | pckA | SHM7688_02923 | SHM7688_00401 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.983 |
bfmBAB | sucC | SHM7688_02923 | SHM7688_03754 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.970 |
bfmBAB | sucD | SHM7688_02923 | SHM7688_03752 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.942 |
bfmBAB | ttuE | SHM7688_02923 | SHM7688_03392 | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.933 |
citZ | bfmBAB | SHM7688_03305 | SHM7688_02923 | Citrate synthase 2; Belongs to the citrate synthase family. | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.957 |
citZ | fumC | SHM7688_03305 | SHM7688_03084 | Citrate synthase 2; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.836 |
citZ | icd_1 | SHM7688_03305 | SHM7688_00123 | Citrate synthase 2; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. | 0.530 |
citZ | maeB_2 | SHM7688_03305 | SHM7688_03627 | Citrate synthase 2; Belongs to the citrate synthase family. | NADP-dependent malic enzyme. | 0.875 |
citZ | mdh | SHM7688_03305 | SHM7688_03756 | Citrate synthase 2; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.961 |
citZ | pckA | SHM7688_03305 | SHM7688_00401 | Citrate synthase 2; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.702 |
citZ | sucC | SHM7688_03305 | SHM7688_03754 | Citrate synthase 2; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.980 |
citZ | sucD | SHM7688_03305 | SHM7688_03752 | Citrate synthase 2; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.817 |
fumC | bfmBAB | SHM7688_03084 | SHM7688_02923 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.724 |
fumC | citZ | SHM7688_03084 | SHM7688_03305 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Citrate synthase 2; Belongs to the citrate synthase family. | 0.836 |