Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cas2-1CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (104 aa)    
Predicted Functional Partners:
CYA_2548
CRISPR-associated protein, TM1812 family; Identified by match to protein family HMM TIGR02221; match to protein family HMM TIGR02549.
 
   
 0.756
CYA_0329
Conserved hypothetical protein; Identified by match to protein family HMM PF05685.
  
     0.599
cas6
CRISPR-associated protein Cas6; Identified by match to protein family HMM TIGR01877.
 
   
 0.576
cas1-1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.572
CYA_0334
Conserved hypothetical protein; Identified by similarity to PIR:AC2464; match to protein family HMM PF05685.
  
     0.532
CYA_0137
Putative membrane protein.
 
     0.478
CYA_0123
Phycobilisome degradation family protein.
  
     0.465
CYA_0938
FHA domain protein; Identified by match to protein family HMM PF00498.
  
     0.455
csx3
CRISPR-associated protein, Csx3 family; Identified by match to protein family HMM TIGR02579.
  
     0.454
CYA_0850
FHA domain protein; Identified by match to protein family HMM PF00498.
  
     0.414
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: low (38%) [HD]