STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsECell division ATP-binding protein FtsE; Identified by similarity to SP:P10115; match to protein family HMM PF00005; match to protein family HMM TIGR02673. (228 aa)    
Predicted Functional Partners:
CYA_0154
Putative permease; Identified by match to protein family HMM PF02687; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.991
macB
Macrolide ABC transporter, permease protein; Identified by similarity to SP:P75831; match to protein family HMM PF02687.
 
      0.897
CYA_1627
Peptidase, M23B family; Identified by match to protein family HMM PF01551.
 
   
 0.594
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.582
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.526
CYA_1895
Peptidase, M23B family; Identified by match to protein family HMM PF01476; match to protein family HMM PF01551.
 
   
 0.510
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
     0.498
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
    0.479
guaA
GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.
  
  
 0.439
panC/cmk
Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
  
  
 0.427
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.