Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobD-1Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (329 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.987
CYA_2240
Putatitve bifunctional adenosylcobalamin biosynthesis protein CobU; Identified by match to protein family HMM PF02283.
 
 
 0.984
cobO-1
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572; match to protein family HMM TIGR00708.
 
  
 0.965
CYA_1473
Putative cob(I)alamin adenosyltransferase.
 
  
 0.952
cobO-2
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572.
 
  
 0.938
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.883
cbiE/cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM PF02390; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
 
  
 0.880
cobK
Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.
 
  
 0.879
cbiG/cobJ-1
cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466; match to protein family HMM TIGR02467.
 
  
 0.873
cbiG/cobJ-2
cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466.
 
  
 0.873
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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