Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CYA_0448CobQ/CobB/MinD/ParA nucleotide binding domain protein; Identified by match to protein family HMM PF01656. (440 aa)    
Predicted Functional Partners:
CYA_0449
Conserved hypothetical protein; Identified by similarity to PIR:S76694.
  
 
 0.938
CYA_0447
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase family protein; Identified by match to protein family HMM PF02779; match to protein family HMM PF03894.
       0.623
CYA_1549
Identified by match to protein family HMM PF00582.
  
    0.578
CYA_1393
TPR repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
 
 0.551
ribAB
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.449
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.446
CYA_0200
Conserved domain protein.
  
     0.434
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.425
CYA_0212
Identified by match to protein family HMM PF00481.
 
    0.420
CYA_0833
Conserved hypothetical protein; Identified by similarity to GB:BAC09852.1.
  
     0.414
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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