Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbiE/cbiTprecorrin-6Y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM PF02390; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. (419 aa)    
Predicted Functional Partners:
cobH-1
precorrin-8X methylmutase; Identified by similarity to GB:CAA04310.1; match to protein family HMM PF02570.
 
 
 0.999
cobH-2
precorrin-8X methylmutase; Identified by similarity to GB:CAA04310.1; match to protein family HMM PF02570.
 
 
 0.998
cobK
Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715.
 
 0.998
cbiG/cobJ-1
cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466; match to protein family HMM TIGR02467.
 
  
 0.997
cbiG/cobJ-2
cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466.
 
  
 0.997
cobM
Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family.
  
 0.994
cobI
Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
 
  
 0.987
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.985
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.941
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Identified by match to protein family HMM PF03602; match to protein family HMM TIGR02469.
 
 
0.933
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: low (14%) [HD]