Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (202 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.988
ureC
Urease, alpha subunit; Identified by similarity to SP:P42885; match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.978
ureD1
Putative urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.970
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
 
 0.952
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.937
CYA_2585
Urease, beta subunit, truncation; Identified by similarity to SP:Q07398.
 
  
 0.857
cobW
Cobalamin biosynthesis protein CobW; Identified by match to protein family HMM PF02492; match to protein family HMM PF07683; match to protein family HMM TIGR02475.
      
 0.561
CYA_1923
Urea ABC transporter, permease protein; Identified by similarity to GB:CAB70949.1; match to protein family HMM PF02653; Belongs to the binding-protein-dependent transport system permease family.
     
 0.430
amt
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
     
 0.408
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.