Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sasAAdaptive-response sensory histidine kinase SasA; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (377 aa)    
Predicted Functional Partners:
CYA_1892
DNA-binding response regulator RpaA; Identified by similarity to GB:AAD30120.2; match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.985
CYA_2739
Response regulator; Identified by match to protein family HMM PF00072.
 
   0.899
CYA_0927
DNA-binding response regulator, LuxR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.896
CYA_1214
DNA-binding response regulator, LuxR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.848
CYA_1392
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
   0.837
CYA_0479
Response regulator; Identified by match to protein family HMM PF00072.
 
 
 0.816
CYA_2336
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF01966; match to protein family HMM TIGR00277.
     0.816
CYA_0796
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.815
CYA_2738
Response regulator; Identified by match to protein family HMM PF00072.
  
   0.800
CYA_2161
Response regulator; Identified by similarity to SP:P43501; match to protein family HMM PF00072.
  
   0.799
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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