STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAAdaptive-response sensory histidine kinase SasA; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (377 aa)    
Predicted Functional Partners:
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.999
CYA_1892
DNA-binding response regulator RpaA; Identified by similarity to GB:AAD30120.2; match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  0.987
CYA_2739
Response regulator; Identified by match to protein family HMM PF00072.
 
   0.909
CYA_0927
DNA-binding response regulator, LuxR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.898
CYA_1392
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
   0.853
CYA_1214
DNA-binding response regulator, LuxR family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.851
CYA_0479
Response regulator; Identified by match to protein family HMM PF00072.
 
 0.838
CYA_2738
Response regulator; Identified by match to protein family HMM PF00072.
 
   0.820
CYA_2161
Response regulator; Identified by similarity to SP:P43501; match to protein family HMM PF00072.
  
   0.819
CYA_0796
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
   0.818
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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