Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobAuroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (252 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 0.976
cobA/hemD
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
 
 
0.934
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.918
cobI
Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family.
    
 0.913
nirA
Ferredoxin-nitrite reductase; Identified by similarity to SP:Q51879; match to protein family HMM PF01077; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.896
cysH
Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.831
sir
Sulfite reductase, ferredoxin dependent; Identified by similarity to SP:P30008; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02042; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.821
CYA_0930
CbiX family protein; Identified by similarity to SP:O87690; match to protein family HMM PF01903.
  
  
 0.785
CYA_0928
Putative membrane protein.
       0.773
hemB
Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.
 
  
 0.714
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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