Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CYA_0972Putative 2`,3`-cyclic-nucleotide 2`-phosphodiesterase; Identified by similarity to SP:P26265; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (553 aa)    
Predicted Functional Partners:
CYA_1059
5'-nucleotidase family protein; Identified by similarity to GB:AAA27331.1; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family.
 
  
  0.970
CYA_1916
Putative adenosine deaminase; Identified by match to protein family HMM PF00962.
    
 0.907
surE-1
Acid phosphatase SurE; Identified by match to protein family HMM PF01975; match to protein family HMM TIGR00087.
     
 0.905
surE-2
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.905
CYA_1715
Conserved hypothetical protein TIGR00726; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
CYA_0973
Conserved hypothetical protein; Identified by match to protein family HMM PF04286.
       0.588
CYA_0117
Identified by match to protein family HMM PF03372.
   
 0.583
CYA_1409
Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304.
   
 0.550
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
       0.458
CYA_0974
Conserved hypothetical protein.
       0.456
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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