| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYA_1032 | CYA_1090 | CYA_1032 | CYA_1090 | Identified by match to protein family HMM PF01743. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.530 |
| CYA_1032 | polA | CYA_1032 | CYA_0531 | Identified by match to protein family HMM PF01743. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.491 |
| CYA_1090 | CYA_1032 | CYA_1090 | CYA_1032 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF01743. | 0.530 |
| CYA_1090 | CYA_1273 | CYA_1090 | CYA_1273 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00814. | 0.977 |
| CYA_1090 | alr | CYA_1090 | CYA_1462 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.549 |
| CYA_1090 | gcp | CYA_1090 | CYA_0297 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.898 |
| CYA_1090 | lgt-1 | CYA_1090 | CYA_1091 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.787 |
| CYA_1090 | murB | CYA_1090 | CYA_1875 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.456 |
| CYA_1090 | nnrE | CYA_1090 | CYA_0088 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...] | 0.739 |
| CYA_1090 | polA | CYA_1090 | CYA_0531 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.523 |
| CYA_1090 | thiL | CYA_1090 | CYA_1899 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.484 |
| CYA_1090 | trmD | CYA_1090 | CYA_1775 | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.564 |
| CYA_1273 | CYA_1090 | CYA_1273 | CYA_1090 | Identified by match to protein family HMM PF00814. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.977 |
| CYA_1273 | gcp | CYA_1273 | CYA_0297 | Identified by match to protein family HMM PF00814. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.933 |
| CYA_1273 | thiL | CYA_1273 | CYA_1899 | Identified by match to protein family HMM PF00814. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.445 |
| alr | CYA_1090 | CYA_1462 | CYA_1090 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.549 |
| alr | murB | CYA_1462 | CYA_1875 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.517 |
| alr | nnrE | CYA_1462 | CYA_0088 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...] | 0.492 |
| gcp | CYA_1090 | CYA_0297 | CYA_1090 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Conserved hypothetical protein TIGR00150; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.898 |
| gcp | CYA_1273 | CYA_0297 | CYA_1273 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Identified by match to protein family HMM PF00814. | 0.933 |