node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYA_1252 | CYA_2348 | CYA_1252 | CYA_2348 | GAF domain protein; Identified by match to protein family HMM PF01590; match to protein family HMM PF01966. | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | 0.572 |
CYA_1252 | pth | CYA_1252 | CYA_1253 | GAF domain protein; Identified by match to protein family HMM PF01590; match to protein family HMM PF01966. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.527 |
CYA_2348 | CYA_1252 | CYA_2348 | CYA_1252 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | GAF domain protein; Identified by match to protein family HMM PF01590; match to protein family HMM PF01966. | 0.572 |
CYA_2348 | guaA | CYA_2348 | CYA_1673 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.487 |
CYA_2348 | mfd | CYA_2348 | CYA_1763 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.474 |
CYA_2348 | pth | CYA_2348 | CYA_1253 | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.694 |
dnaB | guaA | CYA_1550 | CYA_1673 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.660 |
dnaB | pheT | CYA_1550 | CYA_0309 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.640 |
dnaB | prfA | CYA_1550 | CYA_1445 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.551 |
dnaB | pth | CYA_1550 | CYA_1253 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.545 |
guaA | CYA_2348 | CYA_1673 | CYA_2348 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | 0.487 |
guaA | dnaB | CYA_1673 | CYA_1550 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.660 |
guaA | pheT | CYA_1673 | CYA_0309 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.935 |
guaA | pth | CYA_1673 | CYA_1253 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.628 |
guaA | tilS | CYA_1673 | CYA_2591 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.470 |
guaA | ychF | CYA_1673 | CYA_0024 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.742 |
ispH | pth | CYA_1148 | CYA_1253 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.559 |
mfd | CYA_2348 | CYA_1763 | CYA_2348 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. | 0.474 |
mfd | pheT | CYA_1763 | CYA_0309 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | phenylalanyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.461 |
mfd | pth | CYA_1763 | CYA_1253 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.662 |