Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CYA_1383Transcriptional regulator, Fur family; Identified by match to protein family HMM PF01475; Belongs to the Fur family. (149 aa)    
Predicted Functional Partners:
CYA_1382
Putative membrane protein.
       0.773
CYA_1384
Conserved hypothetical protein; Identified by similarity to GB:BAC09596.1.
       0.668
sufR
Iron-sulfur cluster biosynthesis transcriptional regulator SufR; Identified by similarity to PIR:S76597; match to protein family HMM PF08220; match to protein family HMM TIGR02702.
  
    0.530
gltS
Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
     
 0.479
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.471
CYA_2290
Transcriptional regulator, Fur family; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
     0.468
CYA_1386
Conserved hypothetical protein TIGR00303; Identified by match to protein family HMM PF02277; match to protein family HMM TIGR00303; Belongs to the UPF0284 family.
       0.456
CYA_2348
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
  
 0.452
CYA_2836
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF05227; match to protein family HMM TIGR00229.
   
 
 0.444
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00085; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
 
 0.436
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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