Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYA_1473Putative cob(I)alamin adenosyltransferase. (216 aa)    
Predicted Functional Partners:
CYA_2240
Putatitve bifunctional adenosylcobalamin biosynthesis protein CobU; Identified by match to protein family HMM PF02283.
 
 
 0.960
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.960
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.959
cobD-1
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.952
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.930
cobO-2
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572.
  
  
 
0.927
cobO-1
cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572; match to protein family HMM TIGR00708.
  
  
 
0.925
CYA_0510
CobN/magnesium chelatase domain protein; Identified by match to protein family HMM PF02514.
  
 
 0.902
CYA_0724
CobN/magnesium chelatase domain protein.
  
 
 0.902
dcd
Deoxycytidine triphosphate deaminase; Identified by match to protein family HMM TIGR02274.
       0.627
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.