| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYA_0253 | CYA_2779 | CYA_0253 | CYA_2779 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | 0.506 |
| CYA_0253 | kaiA | CYA_0253 | CYA_1902 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | 0.495 |
| CYA_0253 | kaiC | CYA_0253 | CYA_1900 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.595 |
| CYA_1349 | CYA_2779 | CYA_1349 | CYA_2779 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | 0.498 |
| CYA_1349 | kaiA | CYA_1349 | CYA_1902 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | 0.495 |
| CYA_1349 | kaiC | CYA_1349 | CYA_1900 | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.595 |
| CYA_2779 | CYA_0253 | CYA_2779 | CYA_0253 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.506 |
| CYA_2779 | CYA_1349 | CYA_2779 | CYA_1349 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.498 |
| CYA_2779 | kaiA | CYA_2779 | CYA_1902 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | 0.508 |
| CYA_2779 | kaiC | CYA_2779 | CYA_1900 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.589 |
| CYA_2779 | sasA | CYA_2779 | CYA_0637 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | Adaptive-response sensory histidine kinase SasA; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. | 0.411 |
| ftsZ | kaiA | CYA_0109 | CYA_1902 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | 0.462 |
| ftsZ | kaiB | CYA_0109 | CYA_1901 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Circadian clock protein KaiB; Identified by match to protein family HMM PF07689; match to protein family HMM TIGR02654. | 0.549 |
| ftsZ | kaiC | CYA_0109 | CYA_1900 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.560 |
| ftsZ | purF | CYA_0109 | CYA_0277 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.424 |
| ftsZ | recA | CYA_0109 | CYA_1092 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.738 |
| kaiA | CYA_0253 | CYA_1902 | CYA_0253 | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.495 |
| kaiA | CYA_1349 | CYA_1902 | CYA_1349 | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.495 |
| kaiA | CYA_2779 | CYA_1902 | CYA_2779 | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518. | 0.508 |
| kaiA | ftsZ | CYA_1902 | CYA_0109 | Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.462 |