Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kaiACircadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] (304 aa)    
Predicted Functional Partners:
kaiB
Circadian clock protein KaiB; Identified by match to protein family HMM PF07689; match to protein family HMM TIGR02654.
 
 
 
 0.996
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
 
 
 
 0.995
CYA_2000
Conserved hypothetical protein.
  
     0.738
CYA_0635
Conserved hypothetical protein; Identified by similarity to GB:BAC09136.1.
  
     0.723
CYA_0567
Conserved hypothetical protein; Identified by similarity to GB:BAD78868.1.
  
     0.716
CYA_0813
Putative membrane proteinprotein; Identified by similarity to PIR:AH1843.
  
     0.710
CYA_1606
Conserved hypothetical protein; Identified by similarity to GB:BAC08441.1.
  
     0.708
CYA_0867
Conserved hypothetical protein; Identified by similarity to GB:BAC10003.1.
  
     0.707
CYA_1993
Conserved hypothetical protein.
  
     0.706
CYA_0722
Conserved hypothetical protein; Identified by similarity to GB:BAC09253.1.
  
     0.705
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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