Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CYA_1929DnaJ domain protein; Identified by match to protein family HMM PF00226. (230 aa)    
Predicted Functional Partners:
dnaK-1
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.881
CYA_0343
Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family.
  
 0.860
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.859
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 0.851
CYA_2665
DnaJ domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF07719.
  
     0.768
CYA_1134
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
     0.764
CYA_1806
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
     0.763
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
 
 
 0.734
CYA_0342
Conserved hypothetical protein; Identified by similarity to GB:BAC91744.1.
 
 
 0.639
CYA_1927
Conserved hypothetical protein.
       0.553
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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