STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYA_1944RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (760 aa)    
Predicted Functional Partners:
gmk
Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.915
CYA_2432
Putative exopolyphosphatase; Identified by similarity to GB:AAD29107.1; match to protein family HMM PF01966; match to protein family HMM PF02541.
   
 
 0.914
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.910
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
   
 
 0.905
CYA_1210
Pyruvate kinase barrel domain protein; Identified by match to protein family HMM PF00224; Belongs to the pyruvate kinase family.
   
 
  0.900
CYA_2163
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
     
  0.900
nrdJ
Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent, intein-contatining; Identified by match to protein family HMM TIGR01443; match to protein family HMM TIGR01445; match to protein family HMM TIGR02505.
     
  0.900
CYA_2405
Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498.
     
  0.900
ribAB
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
  
 
  0.835
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.800
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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