Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CYA_1963Mandelate racemase/muconate lactonizing enzyme family protein; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746. (349 aa)    
Predicted Functional Partners:
CYA_1962
Conserved hypothetical protein; Identified by match to protein family HMM PF07755.
 
  
  0.995
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
    0.558
CYA_1964
Putative acetolactate synthase, catabolic; Identified by similarity to SP:P27696; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
       0.521
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
   
 0.497
CYA_2294
Antibiotic biosynthesis monooxygenase domain protein; Identified by match to protein family HMM PF03992.
  
     0.474
CYA_2455
Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.
     
 0.470
CYA_0382
Conserved hypothetical protein; Identified by similarity to PIR:AI2167.
  
     0.444
CYA_2328
Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01266.
  
     0.419
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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