| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYA_1944 | CYA_2163 | CYA_1944 | CYA_2163 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | 0.900 |
| CYA_1944 | CYA_2405 | CYA_1944 | CYA_2405 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | 0.900 |
| CYA_1944 | folE | CYA_1944 | CYA_2792 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.800 |
| CYA_1944 | moaA | CYA_1944 | CYA_0172 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.800 |
| CYA_1944 | ndk | CYA_1944 | CYA_1063 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
| CYA_1944 | nrdJ | CYA_1944 | CYA_2169 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent, intein-contatining; Identified by match to protein family HMM TIGR01443; match to protein family HMM TIGR01445; match to protein family HMM TIGR02505. | 0.900 |
| CYA_1944 | ribAB | CYA_1944 | CYA_2473 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.836 |
| CYA_2163 | CYA_1944 | CYA_2163 | CYA_1944 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
| CYA_2163 | CYA_2405 | CYA_2163 | CYA_2405 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | 0.900 |
| CYA_2163 | folE | CYA_2163 | CYA_2792 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.834 |
| CYA_2163 | maf | CYA_2163 | CYA_0360 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Septum formation protein MaF; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.903 |
| CYA_2163 | moaA | CYA_2163 | CYA_0172 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.804 |
| CYA_2163 | ndk | CYA_2163 | CYA_1063 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.903 |
| CYA_2163 | nrdJ | CYA_2163 | CYA_2169 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent, intein-contatining; Identified by match to protein family HMM TIGR01443; match to protein family HMM TIGR01445; match to protein family HMM TIGR02505. | 0.919 |
| CYA_2163 | pyrG | CYA_2163 | CYA_1479 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.906 |
| CYA_2163 | ribAB | CYA_2163 | CYA_2473 | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.802 |
| CYA_2405 | CYA_1944 | CYA_2405 | CYA_1944 | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
| CYA_2405 | CYA_2163 | CYA_2405 | CYA_2163 | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293. | 0.900 |
| CYA_2405 | folE | CYA_2405 | CYA_2792 | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.800 |
| CYA_2405 | moaA | CYA_2405 | CYA_0172 | Putative adenylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF00498. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.803 |