| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYA_1962 | murD | CYA_1962 | CYA_0960 | Conserved hypothetical protein; Identified by match to protein family HMM PF07755. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
| CYA_1962 | murI | CYA_1962 | CYA_2180 | Conserved hypothetical protein; Identified by match to protein family HMM PF07755. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.900 |
| CYA_1962 | purQ | CYA_1962 | CYA_0646 | Conserved hypothetical protein; Identified by match to protein family HMM PF07755. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
| ald | alr | CYA_1112 | CYA_1462 | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.972 |
| ald | gltS | CYA_1112 | CYA_2704 | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.575 |
| ald | murI | CYA_1112 | CYA_2180 | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| alr | ald | CYA_1462 | CYA_1112 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | 0.972 |
| alr | glnA | CYA_1462 | CYA_1363 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | 0.826 |
| alr | murA | CYA_1462 | CYA_1988 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.681 |
| alr | murC | CYA_1462 | CYA_1876 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.798 |
| alr | murD | CYA_1462 | CYA_0960 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.787 |
| alr | murI | CYA_1462 | CYA_2180 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.705 |
| alr | purQ | CYA_1462 | CYA_0646 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.830 |
| glnA | alr | CYA_1363 | CYA_1462 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.826 |
| glnA | gltS | CYA_1363 | CYA_2704 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.978 |
| glnA | murI | CYA_1363 | CYA_2180 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.844 |
| glnA | purQ | CYA_1363 | CYA_0646 | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.909 |
| gltS | ald | CYA_2704 | CYA_1112 | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Alanine dehydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | 0.575 |
| gltS | glnA | CYA_2704 | CYA_1363 | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamine synthetase, type I; Identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653. | 0.978 |
| gltS | murA | CYA_2704 | CYA_1988 | Ferredoxin-dependent glutamate synthase; Identified by similarity to SP:P55038; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.539 |