STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthase; Identified by match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (315 aa)    
Predicted Functional Partners:
CYA_1219
Glutathione S-transferase; Identified by match to protein family HMM PF00043; match to protein family HMM PF02798.
 
  
 0.941
pepA
Peptidase, M17 (leucyl aminopeptidase) family; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.929
ggt
Gamma-glutamyltransferase; Identified by match to protein family HMM PF01019; match to protein family HMM TIGR00066.
     
 0.915
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.805
CYA_0262
Glutamate-cysteine ligase, family 2; Identified by match to protein family HMM PF04107.
 
  
 0.664
CYA_0500
Putative glutamate--cysteine ligase; Identified by match to protein family HMM PF04107; match to protein family HMM TIGR02048.
    
 0.612
CYA_0558
Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily.
  
     0.605
CYA_0979
Identified by match to protein family HMM PF01722; Belongs to the BolA/IbaG family.
  
     0.528
CYA_0923
Transporter, monovalent cation:proton antiporter-2 (CPA2) family; Identified by match to protein family HMM PF00999; match to protein family HMM PF02254; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.521
CYA_2215
Identified by match to protein family HMM PF00805.
       0.493
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: high (86%) [HD]