STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYA_2340Conserved hypothetical protein. (205 aa)    
Predicted Functional Partners:
CYA_2341
Conserved hypothetical protein.
       0.773
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.705
CYA_1013
Conserved hypothetical protein; Identified by similarity to PIR:AH2105; match to protein family HMM PF05685.
  
     0.673
CYA_0334
Conserved hypothetical protein; Identified by similarity to PIR:AC2464; match to protein family HMM PF05685.
  
     0.647
csx3
CRISPR-associated protein, Csx3 family; Identified by match to protein family HMM TIGR02579.
  
     0.608
CYA_0592
Conserved domain protein.
  
     0.577
CYA_0564
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.526
CYA_0329
Conserved hypothetical protein; Identified by match to protein family HMM PF05685.
  
     0.492
CYA_1423
Conserved hypothetical protein; Identified by similarity to PIR:AD2438; match to protein family HMM PF05685.
  
     0.488
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.480
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.