Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CYA_2519RecF/RecN/SMC N terminal domain protein; Identified by match to protein family HMM PF02463. (1198 aa)    
Predicted Functional Partners:
CYA_2520
Identified by match to protein family HMM PF00149.
 
 0.986
CYA_2516
Conserved hypothetical protein; Identified by similarity to GB:BAC07803.1; match to protein family HMM PF01935.
 
     0.946
CYA_2517
Conserved hypothetical protein.
 
     0.946
CYA_2518
Conserved hypothetical protein.
 
   
 0.946
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.845
sbcD
Putative nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.763
CYA_0590
Conserved domain protein.
  
     0.627
CYA_1723
Conserved hypothetical protein; Identified by similarity to GB:BAC10028.1.
  
    0.615
CYA_2628
Putative ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614.
   
 0.608
CYA_1494
Sensor histidine kinase; Identified by match to protein family HMM PF01590; match to protein family HMM PF02518.
  
     0.584
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
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