Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crm2-2CRISPR-associated protein, Crm2 family; Identified by match to protein family HMM TIGR02577. (941 aa)    
Predicted Functional Partners:
cmr6
CRISPR-associated RAMP protein, Cmr6 family; Identified by match to protein family HMM PF03787.
 
 
 
 0.994
CYA_2546
Conserved hypothetical protein; Identified by similarity to GB:BAD01991.1.
 
 
 
 0.977
cmr4
CRISPR-associated RAMP protein, Cmr4 family; Identified by match to protein family HMM PF03787; match to protein family HMM TIGR02580.
 
 
 
 0.968
CYA_2544
Conserved hypothetical protein; Identified by similarity to GB:BAD01988.1.
       0.681
csx3
CRISPR-associated protein, Csx3 family; Identified by match to protein family HMM TIGR02579.
 
     0.671
CYA_2543
Conserved hypothetical protein; Identified by similarity to GB:BAC88877.1; match to protein family HMM PF05685.
 
     0.670
CYA_0507
Conserved hypothetical protein.
  
     0.664
cas2-4
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.628
CYA_1549
Identified by match to protein family HMM PF00582.
  
     0.598
CYA_0199
Prepilin-type N-terminal cleavage/methylation domain protein; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
     0.579
Your Current Organism:
Synechococcus sp. JA33Ab
NCBI taxonomy Id: 321327
Other names: Cyanobacteria bacterium Yellowstone A-Prime, S. sp. JA-3-3Ab, Synechococcus sp. JA-3-3Ab, Synechococcus sp. OS-type A str. JA-3-3Ab, Synechococcus sp. OS-type A strain JA-3-3Ab
Server load: low (12%) [HD]