STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase; Identified by match to protein family HMM PF00316. (332 aa)    
Predicted Functional Partners:
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.962
fba
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.945
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
 
 
 0.940
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342.
   
 
 0.933
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.928
glpX
Fructose-1,6-bisphosphatase, class II; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family.
     
 0.915
CYB_0688
Identified by match to protein family HMM PF01050; match to protein family HMM PF07883.
    
  0.909
CYB_2283
Mannose-6-phosphate isomerase; Identified by match to protein family HMM PF01050; match to protein family HMM PF07883.
    
  0.909
CYB_2162
Kinase, PfkB family; Identified by match to protein family HMM PF00294.
     
 0.904
CYB_1145
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase family protein; Identified by match to protein family HMM PF03894.
     
 0.901
Your Current Organism:
Synechococcus sp. JA23Ba
NCBI taxonomy Id: 321332
Other names: Cyanobacteria bacterium Yellowstone B-Prime, S. sp. JA-2-3B'a(2-13), Synechococcus sp. JA-2-3B'a(2-13)
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