STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSEN2Presenilin 2. (458 aa)    
Predicted Functional Partners:
NCSTN
Nicastrin.
   
 0.999
PSEN1
Presenilin 1.
  
 
0.998
APH1A
Aph-1 homolog A, gamma-secretase subunit.
   
 0.996
TMED10
Transmembrane p24 trafficking protein 10.
    
 0.935
NOTCH1
Notch receptor 1.
    
 0.934
CTNNB1
Catenin beta 1.
    
 0.902
APP
Amyloid beta precursor protein.
    
 
 0.898
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.873
JUP
Junction plakoglobin.
    
 0.832
NOTCH2
Notch receptor 2.
    
 0.789
Your Current Organism:
Lepidothrix coronata
NCBI taxonomy Id: 321398
Other names: L. coronata, Pipra coronata, blue-crowned manakin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.