STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHYPA_030827Histidine kinases. (1070 aa)    
Predicted Functional Partners:
PHYPA_000880
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. In the C-terminal section; belongs to the HisA/HisF family.
   
  
 0.659
PpCLF
Polycomb group protein.
      
 0.651
PHYPA_025957
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
      
 0.621
PHYPA_023111
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
      
 0.621
CRE2
CHASE-domain containing histidine kinase 2.
  
   
0.508
chk3
CHASE-domain containing histidine kinase 3.
  
   
0.501
PpTUA1
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.
     
 0.469
ETR1-2
Ethylene receptor; May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
  
   
0.449
ETR2-2
Ethylene receptor; May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
  
   
0.449
CRE1
Cytokinin receptor 1.
  
   
0.438
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.