STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHYPA_027413Pyruvate kinase; Belongs to the pyruvate kinase family. (612 aa)    
Predicted Functional Partners:
PHYPA_027070
L-lactate dehydrogenase.
  
 0.976
PHYPA_022951
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.976
PHYPA_026044
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.976
PHYPA_015632
Malic enzyme.
  
 0.951
PHYPA_021238
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
 0.915
PHYPA_017757
Uncharacterized protein.
  
 0.907
PHYPA_019273
Uncharacterized protein.
  
 0.901
PHYPA_003653
Uncharacterized protein.
  
 0.901
PHYPA_015567
Uncharacterized protein.
     
  0.900
PHYPA_003948
Uncharacterized protein.
  
 0.895
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.