STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHYPA_026349SurE domain-containing protein. (360 aa)    
Predicted Functional Partners:
PHYPA_024745
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.926
PHYPA_029804
A_deaminase domain-containing protein.
     
 0.921
PHYPA_008386
A_deaminase domain-containing protein.
     
 0.921
PHYPA_001578
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
     
 0.917
PHYPA_019082
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
     
 0.917
PHYPA_017242
IU_nuc_hydro domain-containing protein.
     
  0.912
NRH2
Nucleoside N-ribohydrolase 2.
     
  0.912
PHYPA_028030
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
     
  0.911
PHYPA_025428
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
     
  0.911
PHYPA_014732
A_deaminase domain-containing protein.
     
 0.911
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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