node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | PHYPA_001515 | A0A2K1JVY1 | A0A2K1LAN4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | PHYPA_002659 | A0A2K1JVY1 | A0A2K1L1G3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein; Belongs to the CDC6/cdc18 family. | 0.999 |
MCM7 | PHYPA_011959 | A0A2K1JVY1 | A0A2K1K8G4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM domain-containing protein; Belongs to the MCM family. | 0.999 |
MCM7 | PHYPA_012101 | A0A2K1JVY1 | A0A2K1K1H4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
MCM7 | PHYPA_020197 | A0A2K1JVY1 | A0A2K1JEG1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Zf-primase domain-containing protein. | 0.999 |
MCM7 | PHYPA_023525 | A0A2K1JVY1 | A0A2K1IWQ2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.997 |
MCM7 | PHYPA_024295 | A0A2K1JVY1 | A0A2K1IYX5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | PHYPA_024782 | A0A2K1JVY1 | A0A2K1IU91 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | PHYPA_028326 | A0A2K1JVY1 | A9S5A2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Predicted protein. | 0.999 |
MCM7 | PHYPA_030650 | A0A2K1JVY1 | A0A2K1ID13 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Mcl1_mid domain-containing protein. | 0.995 |
PHYPA_001515 | MCM7 | A0A2K1LAN4 | A0A2K1JVY1 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
PHYPA_001515 | PHYPA_002659 | A0A2K1LAN4 | A0A2K1L1G3 | DNA helicase; Belongs to the MCM family. | Cell division control protein; Belongs to the CDC6/cdc18 family. | 0.997 |
PHYPA_001515 | PHYPA_011959 | A0A2K1LAN4 | A0A2K1K8G4 | DNA helicase; Belongs to the MCM family. | MCM domain-containing protein; Belongs to the MCM family. | 0.554 |
PHYPA_001515 | PHYPA_012101 | A0A2K1LAN4 | A0A2K1K1H4 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
PHYPA_001515 | PHYPA_020197 | A0A2K1LAN4 | A0A2K1JEG1 | DNA helicase; Belongs to the MCM family. | Zf-primase domain-containing protein. | 0.993 |
PHYPA_001515 | PHYPA_023525 | A0A2K1LAN4 | A0A2K1IWQ2 | DNA helicase; Belongs to the MCM family. | Uncharacterized protein. | 0.995 |
PHYPA_001515 | PHYPA_024295 | A0A2K1LAN4 | A0A2K1IYX5 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
PHYPA_001515 | PHYPA_024782 | A0A2K1LAN4 | A0A2K1IU91 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
PHYPA_001515 | PHYPA_028326 | A0A2K1LAN4 | A9S5A2 | DNA helicase; Belongs to the MCM family. | Predicted protein. | 0.995 |
PHYPA_001515 | PHYPA_030650 | A0A2K1LAN4 | A0A2K1ID13 | DNA helicase; Belongs to the MCM family. | Mcl1_mid domain-containing protein. | 0.993 |