STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHYPA_022181HECT domain-containing protein. (1042 aa)    
Predicted Functional Partners:
PHYPA_007488
HECT domain-containing protein.
   
 
0.880
PHYPA_007807
HECT domain-containing protein.
   
 
0.880
PHYPA_020002
U-box domain-containing protein.
   
 
 0.782
PHYPA_014431
RING-type domain-containing protein.
   
 0.725
PHYPA_024362
26S proteasome non-ATPase regulatory subunit 2 homolog; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
    
 
 0.692
PHYPA_023053
26S proteasome non-ATPase regulatory subunit 2 homolog; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
    
 
 0.692
PHYPA_023731
E2_bind domain-containing protein.
   
 
 0.682
PHYPA_025986
Predicted protein.
   
 
 0.682
PHYPA_028790
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
     
 0.680
PHYPA_026874
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.620
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.