node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSEI_0480 | LSEI_0600 | LSEI_0480 | LSEI_0600 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine gamma-synthase. | 0.990 |
LSEI_0480 | LSEI_0624 | LSEI_0480 | LSEI_0624 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.635 |
LSEI_0480 | LSEI_0764 | LSEI_0480 | LSEI_0764 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase II (cobalamin-independent). | 0.906 |
LSEI_0480 | LSEI_1288 | LSEI_0480 | LSEI_1288 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.424 |
LSEI_0480 | LSEI_2151 | LSEI_0480 | LSEI_2151 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Homoserine dehydrogenase. | 0.582 |
LSEI_0480 | LSEI_2183 | LSEI_0480 | LSEI_2183 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.656 |
LSEI_0480 | luxS | LSEI_0480 | LSEI_0765 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Autoinducer AI2 synthesis LuxS-like protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.949 |
LSEI_0480 | metE | LSEI_0480 | LSEI_0625 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.911 |
LSEI_0600 | LSEI_0480 | LSEI_0600 | LSEI_0480 | Cystathionine gamma-synthase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.990 |
LSEI_0600 | LSEI_0624 | LSEI_0600 | LSEI_0624 | Cystathionine gamma-synthase. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.906 |
LSEI_0600 | LSEI_0764 | LSEI_0600 | LSEI_0764 | Cystathionine gamma-synthase. | Methionine synthase II (cobalamin-independent). | 0.955 |
LSEI_0600 | LSEI_1288 | LSEI_0600 | LSEI_1288 | Cystathionine gamma-synthase. | Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.480 |
LSEI_0600 | LSEI_2151 | LSEI_0600 | LSEI_2151 | Cystathionine gamma-synthase. | Homoserine dehydrogenase. | 0.947 |
LSEI_0600 | LSEI_2183 | LSEI_0600 | LSEI_2183 | Cystathionine gamma-synthase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.947 |
LSEI_0600 | luxS | LSEI_0600 | LSEI_0765 | Cystathionine gamma-synthase. | Autoinducer AI2 synthesis LuxS-like protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.933 |
LSEI_0600 | metE | LSEI_0600 | LSEI_0625 | Cystathionine gamma-synthase. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.981 |
LSEI_0624 | LSEI_0480 | LSEI_0624 | LSEI_0480 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.635 |
LSEI_0624 | LSEI_0600 | LSEI_0624 | LSEI_0600 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine gamma-synthase. | 0.906 |
LSEI_0624 | LSEI_0764 | LSEI_0624 | LSEI_0764 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase II (cobalamin-independent). | 0.863 |
LSEI_0624 | LSEI_2151 | LSEI_0624 | LSEI_2151 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine dehydrogenase. | 0.786 |