Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSEI_2799
Cation transport ATPase. (615 aa)
Predicted Functional Partners:
LSEI_0071
Copper chaperone.
0.925
LSEI_0124
Transcriptional regulator, ArsR family.
0.586
LSEI_2800
Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
0.409
Your Current Organism:
Lactobacillus paracasei
NCBI taxonomy Id: 321967 Other names: L. paracasei ATCC 334, Lactobacillus casei ATCC 334, Lactobacillus casei str. ATCC 334, Lactobacillus casei strain ATCC 334, Lactobacillus paracasei ATCC 334