STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB73987.1KEGG: pgt:PGTDC60_1528 6.1e-280 recQ-1; ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97. (727 aa)    
Predicted Functional Partners:
KXB76392.1
UvrD/REP helicase; KEGG: pgi:PG1038 5.3e-210 UvrD/PcrA/Rep family ATP-dependent DNA helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 0.918
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.917
KXB73480.1
DEAD/DEAH box helicase; KEGG: pgn:PGN_2033 2.5e-212 ATP-dependent RNA helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97; Belongs to the DEAD box helicase family.
  
 
0.910
KXB74482.1
KEGG: pgn:PGN_1737 5.4e-185 recQII; ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.896
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 
 0.887
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.876
KXB77973.1
KEGG: tfo:BFO_1535 6.0e-218 DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.856
KXB78540.1
DNA topoisomerase; KEGG: pdn:HMPREF9137_1621 5.5e-247 DNA topoisomerase K03169; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.848
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.820
KXB76388.1
SWIM zinc finger domain protein; KEGG: app:CAP2UW1_3893 2.9e-21 Non-specific serine/threonine protein kinase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.750
Your Current Organism:
Porphyromonas somerae
NCBI taxonomy Id: 322095
Other names: CCUG 51464, DSM 23386, JCM 13867, P. somerae, Porphyromonas somerae Summanen et al. 2006 emend. Hahnke et al. 2016, WAL 6690
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