STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICST_54287Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (291 aa)    
Predicted Functional Partners:
CDC53
Ubiquitin ligase (Cullin) of SCF involved in cell cycle control; Belongs to the cullin family.
   
 0.981
PICST_40298
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.968
HRT1
Skp1 Cullin-F-box ubiquitin protein ligase (SCF) subunit.
    
 0.963
PICST_51711
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.955
COP9
Mov34/MPN/PAD1.
    
 0.888
PICST_34540
Ubiquitin-like domain-containing protein.
    
 0.881
CUL4
Cullin, ubiquitin ligase activity; Belongs to the cullin family.
    
 0.857
PICST_46734
E2_bind domain-containing protein.
    
 0.839
TIP120
TATA-binding protein-interacting protein.
    
 0.786
PICST_73878
Uncharacterized protein.
    
 0.734
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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