STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ILV5Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (399 aa)    
Predicted Functional Partners:
ILV3
Dihydroxyacid dehydratase.
  
 0.992
ILV2
Acetolactate synthase.
 
 
 0.991
ILV6
Acetolactate synthase regulatory subunit.
  
 0.967
ILV1
Threonine dehydratase.
    
 
 0.730
LEU1
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
   
  
 0.694
TUF1
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
     
 0.622
TRP5
Tryptophan synthase.
     
 0.615
PICST_88066
T-complex protein 1 subunit gamma.
      
 0.613
BAT2
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.595
SHM2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
   
  
 0.554
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.