STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URE2Protein URE2; Plays an important role in the cellular response to the nitrogen source; Belongs to the GST superfamily. (311 aa)    
Predicted Functional Partners:
EMC38
Gamma-glutamyltransferase.
     
 0.916
PICST_77026
Thioredoxin domain-containing protein.
   
 0.913
PICST_73480
Regulation of redox homeostasis.
   
 0.913
GLR2
Glutathione reductase (GR) (GRase).
   
 
 0.912
GLR1
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.912
GST2
Glutathione S-transferase; Belongs to the GST superfamily.
  
  
 
0.910
EMC37
Gamma-glutamyltransferase.
     
 0.909
GSH2
Glutathione synthetase.
    
 0.908
GST3
Glutathione S-transferase; Belongs to the GST superfamily.
   
 
 0.906
GST1
Glutathione S-transferase; Belongs to the GST superfamily.
   
 
 0.906
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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