STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COM1Catechol o-methyltransferase. (254 aa)    
Predicted Functional Partners:
SAD1
Secondary alcohol dehydrogenase (SADH1).
  
 
 0.905
SAD2
Secondary alcohol dehydrogenase (SADH2).
  
 
 0.905
ADH1
Alcohol dehydrogenase 1; Converts ethanol to acetaldehyde and plays a major role in xylose fermentation; Belongs to the zinc-containing alcohol dehydrogenase family.
    
 0.904
ADH2
Alcohol dehydrogenase 2; Converts ethanol to acetaldehyde; Belongs to the zinc-containing alcohol dehydrogenase family.
    
 0.904
FDH1
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
     
  0.900
AMO1
Amine oxidase.
     
 0.900
AMO2
Amine oxidase.
     
 0.900
SAM2
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.800
GND1
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
 0.694
ZWF1
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
    
  0.694
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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