STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICST_47673Multicopy suppressor of clathrin deficiency. (499 aa)    
Predicted Functional Partners:
NBM8
NADH-ubiquinone oxidoreductase B18 subunit (Complex I-B18) (CI-B18).
   
   0.510
PICST_9166
Uncharacterized protein.
   
  
 0.498
PICST_76226
NADH-ubiquinone oxidoreductase.
   
    0.483
QCR8
Ubiquinol-cytochrome-c reductase chain VIII.
   
    0.481
RPB10
DNA-directed RNA Polymerase II subunit L.
   
  
 0.479
PICST_90638
Uncharacterized protein.
   
  
 0.477
GLC7
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.459
TIM17
Mitochondrial inner membrane import translocase subunit.
   
 
 0.446
PICST_82538
NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
    0.437
PAN1
Actin cytoskeleton-regulatory complex protein PAN1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
   
 
 0.436
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.