STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRH4ATP-dependent RNA helicase MRH4, mitochondrial; ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA (By similarity); Belongs to the DEAD box helicase family. MRH4 subfamily. (593 aa)    
Predicted Functional Partners:
LSM3
U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 0.836
PRP1
Pre-mRNA splicing factor prp1.
   
 0.769
SNU114
ATP dependent RNA helicase and U5 mRNA splicing factor.
   
 0.751
PICST_88728
Uncharacterized protein.
  
 
 0.721
ATP2
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.709
PICST_35246
Pre-mRNA splicing factor CEF1.
    
 0.708
ETF3
Translation elongation factor.
  
 
 0.703
ATP3
ATP synthase subunit gamma.
   
 
 0.695
RPO41
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
 
 0.654
ATP1
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.635
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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