node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG27 | ATG9 | A3LW83 | A3LZS3 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] | 0.914 |
ATG27 | BGL4 | A3LW83 | A3GH01 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. | 0.470 |
ATG27 | FUC1 | A3LW83 | A3LUK1 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | L-fucose permease Glucose/galactose transporter. | 0.487 |
ATG27 | GAL1 | A3LW83 | A3LR62 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Galactokinase. | 0.599 |
ATG27 | HEX1 | A3LW83 | A3LVC2 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Beta-hexosaminidase. | 0.494 |
ATG27 | INO1 | A3LW83 | A3GI74 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Inositol-3-phosphate synthase (Myo-inositol-1-phosphate synthase) (MI-1-P synthase) (IPS). | 0.412 |
ATG27 | PICST_33238 | A3LW83 | A3LYN4 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Endo/exonuclease/phosphatase domain-containing protein. | 0.487 |
ATG27 | PICST_36882 | A3LW83 | A3LYJ5 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.487 |
ATG27 | TRP6 | A3LW83 | A3LYT4 | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | Anthranilate synthase component II. | 0.648 |
ATG9 | ATG27 | A3LZS3 | A3LW83 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.914 |
BGL4 | ATG27 | A3GH01 | A3LW83 | Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.470 |
FUC1 | ATG27 | A3LUK1 | A3LW83 | L-fucose permease Glucose/galactose transporter. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.487 |
GAL1 | ATG27 | A3LR62 | A3LW83 | Galactokinase. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.599 |
GAL1 | TRP6 | A3LR62 | A3LYT4 | Galactokinase. | Anthranilate synthase component II. | 0.708 |
HEX1 | ATG27 | A3LVC2 | A3LW83 | Beta-hexosaminidase. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.494 |
INO1 | ATG27 | A3GI74 | A3LW83 | Inositol-3-phosphate synthase (Myo-inositol-1-phosphate synthase) (MI-1-P synthase) (IPS). | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.412 |
PICST_33238 | ATG27 | A3LYN4 | A3LW83 | Endo/exonuclease/phosphatase domain-containing protein. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.487 |
PICST_36882 | ATG27 | A3LYJ5 | A3LW83 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.487 |
TRP6 | ATG27 | A3LYT4 | A3LW83 | Anthranilate synthase component II. | Autophagy-related protein 27; Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling. Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a role in ATG protein retrieval from the pre- autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity); Belongs to the ATG27 family. | 0.648 |
TRP6 | GAL1 | A3LYT4 | A3LR62 | Anthranilate synthase component II. | Galactokinase. | 0.708 |