STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRW1DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (514 aa)    
Predicted Functional Partners:
PICST_66631
Uncharacterized protein.
    
 0.973
CUL4
Cullin, ubiquitin ligase activity; Belongs to the cullin family.
    
 0.923
HRT1
Skp1 Cullin-F-box ubiquitin protein ligase (SCF) subunit.
    
 0.848
PICST_47651
Uncharacterized protein.
    
 0.831
COP9
Mov34/MPN/PAD1.
    
 0.817
RFA1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.797
RAD23
Nucleotide excision repair protein (Ubiquitin-like protein).
   
 0.786
RAD14
Zn-binding nucleotide exision repairosome.
    
 0.766
PICST_55239
Uncharacterized protein.
    
 0.762
PICST_31740
WD repeat protein.
    
 0.757
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.