node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASH2 | HHT1 | A3LNQ2 | A3LXD5 | Transcription factor, contains a PHD finger motif. | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.904 |
ASH2 | PICST_31672 | A3LNQ2 | A3LU80 | Transcription factor, contains a PHD finger motif. | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.709 |
ASH2 | PICST_61679 | A3LNQ2 | A3LXD4 | Transcription factor, contains a PHD finger motif. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.930 |
ASH2 | PICST_80251 | A3LNQ2 | A3GGT7 | Transcription factor, contains a PHD finger motif. | Histone deacetylase complex. | 0.480 |
ASH2 | PICST_86017 | A3LNQ2 | A3GGH3 | Transcription factor, contains a PHD finger motif. | DNA damage-responsive transcriptional repressor RPH1. | 0.434 |
ASH2 | SET1 | A3LNQ2 | A3LX95 | Transcription factor, contains a PHD finger motif. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.998 |
ASH2 | SET5 | A3LNQ2 | A3M0J3 | Transcription factor, contains a PHD finger motif. | Potential protein lysine methyltransferase SET5; Putative protein lysine methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily. | 0.628 |
ASH2 | SWD1 | A3LNQ2 | A3LP31 | Transcription factor, contains a PHD finger motif. | Chromatin binding protein. | 0.999 |
HAT2 | HHT1 | A3LWN8 | A3LXD5 | Histone acetyltransferase subunit. | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.843 |
HAT2 | PICST_31672 | A3LWN8 | A3LU80 | Histone acetyltransferase subunit. | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.484 |
HAT2 | PICST_61679 | A3LWN8 | A3LXD4 | Histone acetyltransferase subunit. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.984 |
HAT2 | SET1 | A3LWN8 | A3LX95 | Histone acetyltransferase subunit. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.488 |
HAT2 | SET5 | A3LWN8 | A3M0J3 | Histone acetyltransferase subunit. | Potential protein lysine methyltransferase SET5; Putative protein lysine methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily. | 0.541 |
HAT2 | SWD1 | A3LWN8 | A3LP31 | Histone acetyltransferase subunit. | Chromatin binding protein. | 0.548 |
HHT1 | ASH2 | A3LXD5 | A3LNQ2 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Transcription factor, contains a PHD finger motif. | 0.904 |
HHT1 | HAT2 | A3LXD5 | A3LWN8 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone acetyltransferase subunit. | 0.843 |
HHT1 | PICST_31672 | A3LXD5 | A3LU80 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.949 |
HHT1 | PICST_61679 | A3LXD5 | A3LXD4 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.998 |
HHT1 | PICST_80251 | A3LXD5 | A3GGT7 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone deacetylase complex. | 0.516 |
HHT1 | PICST_86017 | A3LXD5 | A3GGH3 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | DNA damage-responsive transcriptional repressor RPH1. | 0.993 |