STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFD96078.1ABC-2 type transport system permease protein. (532 aa)    
Predicted Functional Partners:
SFD96048.1
ABC-2 type transport system ATP-binding protein.
 
    0.958
msrA
methionine-R-sulfoxide reductase/methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.636
lysS
lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.592
mprF
Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
    
  0.554
SFE44275.1
Fucose 4-O-acetylase.
 
   
 0.489
SFE42723.1
AraC-type DNA-binding protein.
  
    0.479
SFD86313.1
Hypothetical protein.
  
     0.437
Your Current Organism:
Sharpea azabuensis
NCBI taxonomy Id: 322505
Other names: DSM 18934, JCM 14210, Lactobacillus sp. DI49, Lactobacillus sp. HM244, Lactobacillus sp. HM250, Lactobacillus sp. ST#18, S. azabuensis, Sharpea azabuensis Morita et al. 2008, strain ST18
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.