STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACO76447.1NAD(P) transhydrogenase, subunit alpha part 2. (102 aa)    
Predicted Functional Partners:
ACO76446.1
NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 
 0.999
ACO76448.1
NAD(P) transhydrogenase, subunit alpha part 1.
 
 0.999
nadK
ATP-NAD kinase protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.919
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.917
nadE
Glutamine-dependent NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.909
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.907
cobB
Transcriptional regulator Sir2 family protein; Belongs to the sirtuin family. Class III subfamily.
     
 0.904
ACO79473.1
NAD-dependent deacetylase, Sir2-family protein.
     
 0.904
mazG
Nucleotide pyrophosphohydrolase MazG.
    
  0.901
nudC
NADH pyrophosphatase; Belongs to the Nudix hydrolase family. NudC subfamily.
     
  0.900
Your Current Organism:
Azotobacter vinelandii
NCBI taxonomy Id: 322710
Other names: A. vinelandii DJ, Azotobacter vinelandii DJ, Azotobacter vinelandii str. DJ, Azotobacter vinelandii strain DJ
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.